Tuesday, December 05, 2006

Winter Blues

Personal Health

Getting a Grip on the Winter Blues

Published: December 5, 2006

It is that time of year again, when despite the ratcheting up of festivities for the holidays, fully one person in five in the United States ratchets down. The cause is a now well-known but still infrequently treated disorder, winter blues or SAD, for seasonal affective disorder.

There are several remedies to help those affected by SAD escape an affliction that leaves many wanting to climb into bed, put their heads under the covers and not come out until spring. Indeed, some experts refer to SAD as a form of hibernation.

The problem typically starts gradually as the days become shorter in late summer or fall and peaks in midwinter in regions where there may be just 9 or 10 hours of daylight, if that.

For the estimated 14 million severely affected American adults, SAD can send them into a tailspin that makes it difficult if not impossible to fulfill daily responsibilities and derive any joy from life. An additional 33 million people are less severely affected but may experience declines in energy, cheerfulness, creativity or productivity in the dark days of winter.

The most commonly used treatment is exposure for up to several hours a day to high-intensity artificial light, in an effort to simulate the longer days of summer when people with SAD function at top speed.

Jet Lag and Circadian Rhythm

Dr Alfred J. Lewy, a psychiatrist who has been studying the biology behind SAD, describes it as a form of jet lag, a concept he proposed 20 years ago. He recently published experimental evidence that he says attests to the validity of this theory. If true, this would make SAD a disturbance in the circadian rhythm, the 24-hour pattern that normally aligns the sleep-wake cycle with all the other bodily rhythms. Dr. Lewy suggests that with the delayed dawn and shorter days of fall and winter, the rhythms of people afflicted with SAD drift out of phase with the sleep-wake cycle, as if they had traveled across many time zones.

With jet lag, recovery occurs over a matter of days, and the circadian rhythm once again becomes synchronized with day and night. “In people with SAD, this adjustment takes five months,” Dr. Lewy said.

If his theory is substantiated by further research, it may one day be possible to treat SAD with tiny daily doses of time-released melatonin, the substance in the brain that regulates the sleep-wake cycle. Melatonin naturally increases in the evening, causing sleepiness, and falls off as morning approaches. The idea would be to tailor the administration of melatonin in a way that realigns the out-of-sync circadian rhythm in people with SAD, just as tiny doses (much smaller than those typically sold in health-food and drug stores) of melatonin can be used to speed recovery from jet lag.

In his study, conducted with three colleagues at Oregon Health Sciences University, Dr. Lewy identified two types of SAD patients. About two-thirds required morning light or evening melatonin to correct their body clocks. The remainder needed evening light or morning melatonin to put their body rhythms back on track. Currently, there is no commercial source of time-release low-dose melatonin that could be used, with or without light therapy, to help people with SAD.

Current Remedies

Dr. Norman E. Rosenthal, a native of South Africa who discovered his own serious problem with SAD while a resident in psychiatry at the New York State Psychiatric Institute in 1976, has become an expert in diagnosing and treating the problem. His knowledge and experience in helping himself and countless patients afflicted with SAD are summarized in “Winter Blues: Everything You Need to Know to Beat Seasonal Affective Disorder,” whose revised edition the Guilford Press published this year.

Dr. Rosenthal aptly describes SAD as “an energy crisis.” Patients are not depressed in the usual emotional sense, but rather feel as if their batteries have run down.

The symptoms of SAD do mimic those of serious depression. Patients say they have to drag themselves out of bed in the morning, even after 10 hours of sleep, and force themselves to perform necessary chores. They feel leaden and would just as soon not see anybody or do anything. They find it difficult to concentrate and think clearly and quickly.

Sex drive often dwindles markedly but is often replaced by an insatiable appetite for carbohydrates — breads, pasta, potatoes, rice and sweets — that results in weight gain. Many people with SAD have two wardrobes, the one for winter being two sizes larger.

The most common remedy is light therapy. But not just any light. Patients are advised to sit in front of a specially designed light box that emits about 10,000 lux from a fluorescent bulb, most often in the morning for at least 45 minutes. Some patients require hours of light therapy each day to ward off the symptoms of SAD, which may mean having one light box at home and a second at work.

Among commercial sources for these light boxes is the Center for Environmental Therapeutics, which sells them for $200. Its Web site, www.cet.org, is a useful source of information about SAD.

Among other light-enhancing suggestions from Dr. Rosenthal are planning a winter vacation in a sunny climate or relocating to someplace nearer the Equator, where the days are longer in winter. (But, he cautions, first be sure you can tolerate the summer there.)

Helpful Machines and Therapies

For those who remain in northern latitudes, Michael and Jiuan Su Terman of the New York State Psychiatric Institute at Columbia University, who have conducted pioneering studies of SAD remedies, suggest considering a “dawn simulator.” This device gradually turns on a bedroom light every morning while you are still asleep, helping ease SAD symptoms by making the body think that it is experiencing the early sunrises of summer.

This might also help people who do not have SAD but who hate getting up in the morning when it is still dark out.

The Termans have also found another helpful gadget, a negative-ion generator. They showed that sitting in front of a machine that emits negative ions at a high rate for 30 minutes every morning was as effective as sitting in front of a light box for the same time. The generators are available for $165 from the Center for Environmental Therapeutics (Michael Terman is the president of its board). The advantage of this device is that it can be used while sleeping.

A third approach that has proved effective is cognitive behavioral therapy, when used with or without light therapy. Kelly J. Rohan of the Uniformed Services University of the Health Sciences in Bethesda, Md., found that this therapy, a brief form of psychotherapy that helps people change negative thoughts and behaviors, was as effective as light therapy in a study of 23 patients with SAD.

And unlike light therapy used alone, cognitive behavioral therapy helped prevent a relapse of SAD symptoms the next winter.

Dr. Rosenthal also recommends eating a diet relatively high in protein and low in carbohydrates and performing regular physical exercise, which is especially helpful if it is outdoors in the morning or, if indoors, in front of a light bo

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Monday, December 04, 2006

Future of Newspapers

A Newspaper Chain Sees Its Future, And It's Online and Hyper-Local

Washington Post Staff Writer
Monday, December 4, 2006; Page A01

FORT MYERS, Fla. -- Could this be the future of newspapering?

Darkness falls on a chilly Winn-Dixie parking lot in a dodgy part of North Fort Myers just before Thanksgiving. Chuck Myron sits in his little gray Nissan and types on an IBM ThinkPad laptop plugged into the car's cigarette lighter. The glow of the screen illuminates his face.


Myron, 27, is a reporter for the Fort Myers News-Press and one of its fleet of mobile journalists, or "mojos." The mojos have high-tech tools -- ThinkPads, digital audio recorders, digital still and video cameras -- but no desk, no chair, no nameplate, no land line, no office. They spend their time on the road looking for stories, filing several a day for the newspaper's Web site, and often for the print edition, too. Their guiding principle: A constantly updated stream of intensely local, fresh Web content -- regardless of its traditional news value -- is key to building online and newspaper readership.

Myron and his colleagues are part of a great experiment being conducted by their corporate parent, McLean-based newspaper giant Gannett, which is trying to remake the very definition of a newspaper. Losing readers and revenue to the Internet and other media, newspapers are struggling to stay relevant and even afloat. Gannett's answer is radical.

The chain's papers are redirecting their newsrooms to focus on the Web first, paper second. Papers are slashing national and foreign coverage and beefing up "hyper-local," street-by-street news. They are creating reader-searchable databases on traffic flows and school class sizes. Web sites are fed with reader-generated content, such as pictures of their kids with Santa. In short, Gannett -- at its 90 papers, including USA Today -- is trying everything it can think of to create Web sites that will attract more readers.

"Whatever you spend your time and money doing," said News-Press managing editor Mackenzie Warren, "is news."

So Myron sits in the parking lot, hunched over, keeping one eye out for threatening vagrants, and peers through his steering wheel to file a story on his laptop, perched on his knees. The workplace is, at best, ergonomically challenging.

The event he just covered? The signing of a fundraising calendar for the local chamber of commerce featuring the Hunks of North Fort Myers. The event was held inside a gym beside a Winn-Dixie in a strip shopping center.

It had been looking dim -- just three hunks and half a dozen seemingly uninterested middle-aged ladies working out nearby -- when Myron arrived at the gym with his ThinkPad under one arm and a digital camera peeking out of a pocket of his khakis.

Twenty minutes passed before one senior citizen and her husband walked in with two calendars to be signed by the hunks. She agreed to be interviewed and have her picture taken by Myron. He took notes on the screen of his ThinkPad, using an electronic stylus.

Thirty minutes later, sitting in his car with a sense of relief, he has written a short story, cropped one digital picture, written a caption, uploaded it all to the Web and linked to a previous story he'd written on the calendar fundraiser. Traditionally, such a story would barely rise to the level of a newspaper's weekly community insert. Yet this is the third story Myron has written on the calendar.

In the dark, Myron refreshed his browser and pulled up his fresh dispatch on the News-Press's Cape Coral "micro-site," one of several sites-within-a-site focusing on individual communities.

"There it is," he said. "That's what I do."

Fort Myers is a growing city constantly replenished by hard-core newspaper readers -- retirees. As such, the News-Press, circulation 89,283, has been spared some of the tumult in the rest of the newspaper industry, where circulation and advertising revenue have been in steady slide for a decade. Gannett's stock price is down 25 percent over the past two years. Hence the overhaul.


"We're trying a lot of things. Some will work; others won't," said Kate Marymont, 53, the energetic News-Press executive editor for the past six years and a Gannett lifer. "It's like play."

Among her innovations are some ideas that challenge journalistic orthodoxy. For instance:

? The creation of 14 full- and part-time mojos. By the end of next year, the paper's 30 other news reporters also will be mojos to one extent or another. The News-Press is nonunion.

? Enlisting the help of dozens of reader experts -- retired engineers, accountants, government insiders -- to review documents and data to determine why it costs so much to hook up water and sewer service to new homes in the area. The result: an investigative report that resulted in fees lowered by 30 percent and an official ousted. Gannett calls the practice "crowdsourcing." The News-Press and other Gannett papers also are building searchable online databases on as many topics as they can think of, in part to "enable people to do digging themselves and maybe find conclusions we won't," said Michael Maness, Gannett's vice president of strategic planning. "It's having thousands of investigative reporters instead of three."

? The appointment of a managing editor in charge of "audience building" who reports only to Marymont. The editor monitors Web traffic to make sure popular stories stay high on the page. The editor meets weekly and shares data with the paper's marketing and sales staffers.

? Online message boards that allow readers to post anything from lost-pet notices to profanity. "Bring it on," Warren said.

? Next spring, the paper plans to run a large story on a topic it would not identify. It did, however, say that the reporter on the article will accompany News-Press ad salespeople on trips to advertisers as the paper seeks a sponsor for the article. The logic: The reporter understands the project and can explain it best to potential advertisers. Though the reporter will be in sales meetings, he or she will not be part of the sales pitch. Nevertheless, the practice violates one of journalism's fundamentals -- maintaining a leakproof wall between the news and business sides of a newspaper.

As part of their training, mojos get a three-hour session with the paper's vice president of marketing. If someone out in the community complains that ad rates are too high in the daily News-Press, mojos can and should tell them that rates are lower in the paper's community weeklies.

It would be "morally wrong" for a reporter not to pass along such information, said Warren, the managing editor for information distribution, a new position. The paper also has a managing editor for information collection.

"It's like rolling down your window and giving someone directions," Warren said. Keeping reporters away from the business side is "old-school snobbery," he said.

The newsroom has mixed opinions of the new ways. Many are enthusiastic. "There is so much more creative energy than we can harness into actual journalism so far," said managing editor Cindy McCurry-Ross. Others are irked by such practices as mojos posting stories directly to the Web without editing -- a breach of newspaper editing protocol.

"It makes me crazy," said Gale Baldwin, a News-Press assistant managing editor and newspaper veteran. "But I grit my teeth because I know that things are changing."


Some staffers, who spoke on condition of anonymity for fear of retribution, worry that the zeal to feed the Web with fresh material has led to publishing "fluff" in addition to news. They recalled one recent incident in which Marymont walked through the newsroom and strongly noted that the Web site had not posted any fresh material in three hours, and urged them to publish something quickly.

Though the News-Press has largely been insulated from the industry's travails, it has not been immune. The paper showed a circulation decline this year, and Marymont must eliminate three staff positions by the end of the year to meet the budget set by Gannett headquarters in McLean. The paper has offered buyouts to older staffers.

Are readers buying the changes?

On the one hand, the News-Press Web site had grown from an average of 58,000 unique visitors per week in 2002 to 140,000 per week so far this year. Traffic to the paper's community micro-sites in August-October of this year is up 106 percent over the corresponding period last year. Carol Hudler, the paper's publisher, said it's too early to tell if the changes have made a material impact on the paper's revenue.

On the other hand, none of the sources Myron dealt with in two assignments on consecutive days seemed to grasp that what he was reporting and writing about them would go to the News-Press Web site.

"They ask me, 'When's what you wrote about me going to be in the paper?' " Myron said. "I have no good answer."



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Saturday, December 02, 2006

Weight = Loss

Your Money

Extra Weight, Higher Costs

Published: December 2, 2006

As you snatch a couple more Christmas cookies or down another eggnog, you might be thinking about what those extra calories will do to your health.

But have you considered what they will do to your wealth? The sugar and fat will add pounds, which can lead to heart disease, diabetes and a shortened life span.

There is another consequence to packing on extra weight: being fat costs money — tens of thousands of dollars over a lifetime.

Heavy people do not spend more than normal-size people on food, but their life insurance premiums are two to four times as large. They can expect higher medical expenses, and they tend to make less money and accumulate less wealth in their shortened lifetimes. They can have a harder time being hired, and then a harder time winning plum assignments and promotions.

We’re not talking about people who are merely carrying a few extra pounds, or only those who are Jabba the Hutt in their dimensions, either. People carrying 30 to 40 pounds extra can be affected.

“Being overweight can be dangerous to your wealth,” said Jay L. Zagorsky, an economist at Ohio State University who has looked at the relationship between various economic and sociological factors and a measure of obesity called the body mass index.

Doctors use the index to determine whether a person is merely overweight or dangerously obese. You divide your weight in pounds by the square of your height in inches, which is then multiplied by 703, to adjust the English-system measurements to the metric system. (You could use kilograms and centimeters, but that would be too easy.) Or use a Web calculator like the one at www.nhlbisupport.com/bmi/ or www.halls.md/ideal-weight/body.htm.

Anything under 25 is considered a normal reading of the index. From 25 to 30 is overweight, and above 30 is obese. People who rate above 40 are considered morbidly obese, meaning they are facing serious and sustained health problems.

The index has been criticized for its inability to distinguish between a well-muscled person and a fat one. Nevertheless, it is by this measure that academics estimate that 97 million Americans, about a third of the population, are considered obese. Almost 10 million Americans could be considered morbidly obese.

Academics have struggled to place a price tag on the cost of treating those carrying around too much weight. The obese suffer from heart disease, diabetes, depression, arthritis and joint problems, liver disease and sleep apnea.

Complications from obesity, particularly diabetes, which afflicts 21 million Americans, push up the bill: $44,000 for a heart attack, $40,200 for a stroke or $37,000 for end-state kidney disease, estimates Judith A. O’Brien, the director of cost research at the Caro Research Institute, a health costs consulting firm. Amputating just a toe, a not uncommon consequence of untreated diabetes, averages $15,000, she estimates.

Academics have not spent much time calculating what that care costs the overweight individual. Instead, they look at what obesity costs society or insurers. The sum usually arrived at is about $80 billion a year and steadily growing. The government or insurers pay about 85 percent of that. In other words, the fit and the fat pay for it indirectly through taxes or higher health insurance premiums.

This year, two nutritional scientists at the University of Wisconsin-Madison, Rachel N. Close and Dale A. Schoeller, took a unique twist on the calculations to determine what “supersizing” a fast-food meal costs society. Paying 67 cents to supersize an order — 73 percent more calories for 17 percent more money — adds an average of 36 grams of adipose tissue. The future medical costs for that bargain would be $6.64 for an obese man and $3.46 for an obese woman. “The hidden financial costs associated with weight gain from upsizing a value meal may help convince people it is not a bargain,” Mr. Schoeller said.

Even routine care can put a dent in a family’s finances. Office visits and prescriptions for medicines to manage diabetes, high cholesterol, back pain and depression can reach $7,000 in annual out-of-pocket expenses for someone — admittedly one with nearly every problem associated with obesity — covered by an employer’s health insurance, according to an online health care cost estimator United HealthGroup provides to its customers.

While the health problems ravage savings, an overweight person may have difficulty accumulating a nest egg in the first place. One of the earliest sociological studies of the overweight, in 1966, found that the heaviest students had a harder time getting into top colleges. More recent studies have found that the obese, particularly white women, are paid less. A study by John H. Cawley, an associate professor of human ecology at Cornell University, found that a weight increase of 64 pounds above the average for white women was associated with 9 percent lower wages.

Evidence from decades of discrimination studies has led Mark V. Roehling, an associate professor at the School of Labor and Industrial Relations at Michigan State University, to the conclusion that there is “consistent evidence of weight discrimination.”

One factor is that some employers do not want to be burdened with higher health insurance costs. Other times it is a matter of appearances or a belief that “people of size,” as Mr. Roehling terms the obese, are lazy, weak-willed or considered too unattractive to interact with customers. He has found that some employers are upfront about it, even in Michigan, which is the only state that outlaws weight discrimination.

While conducting research, he said, he was told by a personnel manager, who himself was overweight, that the company would not hire overweight people, even after Mr. Roehling told him that was illegal. The bias is more pronounced toward white women than white men, Mr. Roehling said: “Blacks are more accepting of large people and whites are more accepting of overweight black females.”

Mr. Roehling is convinced that weight bias is stronger than bias stemming from race. You can test that thesis yourself with the Implicit Association Test, at implicit.harvard.edu/implicit. It was created by researchers at Harvard, the University of Virginia and the University of Washington to plumb an individual’s attitude toward race, ethnicity and religion. Take the test for prejudice against overweight people and compare your result against the similar test for race.

Brian A. Nosek, a psychology professor at the University of Virginia who helped develop it, said that test results showed that bias against blacks and the overweight was about equal, but that while people rarely admit to race bias, they freely admit to weight bias. “There is no social sanction against saying you don’t like fat people,” Mr. Nosek said.

The weight penalties come in other forms as well. Sociologists have long noted that in developed countries, the higher-status people tend to be thin and the lower- status ones are fat. “That heavier people have a harder time getting married is pretty well supported,” said Jeffery Sobal, a professor at Cornell University who has studied obesity. Marriage can be crucial in wealth creation, especially when a person “marries up” to someone with money or a higher education. That may be a rarer occurrence for the obese. “There is a stigma against the overweight that plays out in the social class world,” he said.

The end result? The obese accumulate only about half the assets of the normal-size American, said Mr. Zagorsky, the Ohio State University research scientist. He matched B.M.I. and wealth data in the National Longitudinal Survey of Youth, a multiyear sampling done by the Bureau of Labor Statistics, and found that for every one-point increase in the index, net worth dropped by $1,000. The typical female baby boomer, he said, earned $313.70 less annually for every one-point increase in her B.M.I., while the typical male earned $161.30 less for every point.

A chicken-or-egg question invariably pops up. Are people fat because they are poor or poor because they are fat?

“We can never prove causality in social science,” Mr. Zagorsky said. “As an experiment, I can’t force people to eat or force them not to eat.” But he said that if wealth causes the change in weight, then people who receive inheritances should show a corresponding drop in their B.M.I. That does not happen, so he asserts that weight drives the lack of wealth.

Mr. Zagorsky’s data revealed an odd finding about inheritances. Thin people tend to receive bigger inheritances. He is not sure why, but he thought it could be because people with low B.M.I.’s live longer and their parents tend to live longer, so wealth has a longer time to accumulate before it is transferred.

What happens to a person who loses weight? Mr. Zagorsky said a drastic drop in weight corresponds to an increase in wealth. A baby boomer whose B.M.I. drops from 27.5, the middle of the overweight category, to 21.7, the middle of the normal category, sees an increase in wealth of $4,085. The impact of weight loss on wealth was considerably less for black women and it appeared to make no difference for black men. But a B.M.I. decrease of 10 points corresponds to a wealth increase of $12,720 for white men and slightly less for white women.

But it has to be a big loss in weight. “You can’t just drop 10 pounds and change your wealth,” he said.

E-mail: yourmoney@nytimes.com



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Wednesday, November 29, 2006

Living Will

Personal Health

Medical Due Diligence: A Living Will Should Spell Out the Specifics

Published: November 28, 2006

When I ask people whether and how they have made preparations for the ends of their lives, the most frequent response is, “Well, I have a living will.” But chances are they are unaware of the serious limitations inherent in such a document and how it is likely to be interpreted by medical personnel should a life-threatening crisis arise.

A living will is an advance directive, a document that states your wishes about how you should be cared for at the end of your life. It is meant to be activated when you are unable to say what you do or do not want to be done medically — if, for example, you are in a terminal condition, your heart and breathing cease, you are in a persistent vegetative state because of severe brain damage or you are too demented to understand the situation.

A living will lists your general preferences for or against life-prolonging treatment like cardiopulmonary resuscitation if your heart suddenly stops, or mechanical respiration if you cannot breathe well enough on your own. But the simple statements contained in most living wills, more often than not, are hard to apply to the great variety of medical situations that can arise.

For example, let’s say you’re a 70-year-old active retiree with congestive heart failure who develops pneumonia and has trouble breathing. You go to the emergency room, living will in hand, stating that if you become terminally ill, you do not want to be treated with antibiotics or placed on a ventilator.

Open to Misinterpretation

The admitting physician reading your living will may interpret it as a “do not resuscitate,” or D.N.R., statement, meaning you want no treatment for your life-threatening infection, in which case you would probably die. Yet a course of antibiotics and a week or so with assisted breathing could restore you to your previously active state.

Dr. Ferdinando L. Mirarchi, chairman of emergency medicine at Hamot Medical Center in Erie, Pa., tells of a very active 64-year-old woman who nearly died because a nurse read her living will as a D.N.R. statement. The woman had slipped on ice and broken a leg, which was reset surgically. On the second postoperative day she began bleeding in her abdomen, and excreted and vomited blood. But the nurse saw her living will and told the physician on call that she was D.N.R. and thus did not warrant admission to the intensive care unit. Fortunately, another physician overrode the nurse’s interpretation and resuscitated the woman, who successfully underwent emergency surgery to stop the bleeding.

Living wills became popular — and were established as legally binding documents in all states except New York, Massachusetts and Michigan — after personal experiences and highly publicized cases like that of Terri Schiavo demonstrated the futility of prolonging lives that met few people’s definition of living.

Countless billions of dollars have been spent to support the hearts and lungs of people who will never leave the hospital alive. Many people, appalled by these torturously medicalized deaths, completed a notarized document to prevent this when they neared the end of their lives. About 20 percent of the population has a living will. But will it really help, or might it harm?

An Improved Document

Dr. Mirarchi (pronounced mir-AR-ki) has studied how health professionals interpret living wills and found that the overwhelming majority think they mean that the patient wants to be treated as D.N.R., when in fact aggressive life-saving interventions could restore some patients to their previous state of health.

Accordingly, he has devised a more comprehensive living will — an advance directive he calls a medical living will with “code status” — that people can fill out in consultation with their physicians and perhaps an attorney to help assure they get the kind of care they would want if they could ask for it. The “code status” tells medical personnel exactly how someone wants to be treated in a life-threatening medical emergency, removing the guesswork.

If, for example, you choose “full code,” the directive would say: “I would like to receive all lifesaving and supportive measures should an emergency arise. Should my condition fail to improve and I am no longer able to make my own decisions, then I would like my advance directive to be active and followed.”

Only at that point, then, would individually stated requests be honored, such as not being resuscitated, defibrillated, ventilated, fed by tube, transfused, given antibiotics or placed on a dialysis machine.

You could also choose “full code except cardiac arrest,” meaning that all measures short of restarting your stopped heart should be tried. Or let’s say you are a terminally ill cancer patient and recognize the futility of continued treatment. You could choose “comfort care, hospice care” and have only your symptoms treated to ease your departure from this life. Dr. Mirarchi’s reasons for the revised living will are spelled out in his forthcoming book, “Understanding Your Living Will: What You Need to Know Before a Medical Emergency” (Addicus Books).

Dr. Mirarchi strongly recommends that people periodically review and update their living wills as needs and medical conditions change. He points out that if you choose to be an organ donor, your living will should state that and give permission to temporarily suspend the document to preserve the viability of your organs.

Medical consultants writing in Patient Care (Nov. 15, 2000) noted that “the less inclusive a living will is, the more trouble it can cause.” Doctors may be uncomfortable following vague directives. The consultants suggested that living wills could be more useful if the directives were disease specific. For example, if you have emphysema, you may want to accept antibiotics and mechanical ventilation if you develop pneumonia, but you may not want such treatment if you are near death from cancer.

Your living will should also state that you (or your heirs) will not sue health care workers or facilities for following your stated wishes. The document can also call for a two-physician conference before life-prolonging treatments are withdrawn. The final document should be notarized.

Make several copies of your completed living will. File them with your personal physician or local medical center, your next of kin and attorney, and include a copy with your medical records and your last will and testament. You might also carry a wallet-size card stating your chosen “status code,” emergency information and name and phone number of your health care proxy.

Have a Health Care Proxy, Too

As may already be apparent, it is not enough to have a living will. You should also assign someone you trust to voice your medical wishes when you cannot speak for yourself. That person should first have a detailed conversation with you about how you want to be treated under various circumstances and also have a copy of your living will.

It may be best if that person has no vested interest in your estate and is younger than you. In most states, the health care proxy is recognized as acting for the patient, compelling medical personnel to follow the proxy’s instructions.

Finally, it should also be obvious that both a living will and a health care proxy should be in place as soon as a person turns 18 and becomes an adult in the eyes of the law. You never know how old or healthy you may be when its instructions are needed. Ms. Schiavo was only 26 when she suffered a brain-damaging cardiac arrest.



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Asthma

Second Opinion

An Epidemic No One Understands

Published: November 28, 2006

When our first son developed asthma as a 3-year-old, my husband and I felt pretty much blindsided. We were only a little less shocked when the same thing happened to our second son, at the same age.

The disease turned out to be tenacious, and for years both boys needed inhalers or a nebulizer machine several times a day to prevent asthma attacks that could keep them up half the night, coughing and wheezing.

Both had eczema, too, and the kind of food allergies — to nuts, peanuts and shellfish — that can lead to fatal reactions.

What caused all this? My husband and I were mystified, because neither of us had asthma or life-threatening allergies, nor did our parents or siblings. I do have hay fever and allergies to cats and dogs, but I had always considered my symptoms just a nuisance — not a bad omen for the next generation. My husband isn’t allergic to anything.

But we seem to have been caught on a rising tide that no one fully understands. Our sons were born in 1984 and 1987, and we encountered an awful lot of children their ages who had the same illnesses, far more than we remembered from our own generation.

Statistics suggest that something strange was occurring in those years. From 1980 to 2003, the prevalence of asthma in children rose to 5.8 percent from 3.6 percent, an increase of about 60 percent, according to the Centers for Disease Control and Prevention.

Other estimates from the disease centers show an even bigger increase in the asthmas rates for younger children: a 160 percent jump in those younger than 5 from 1980 to 1994. But changes in data collection starting in 1997 make it hard to compare the figures before and after that year. More recently, the rates seem to have leveled off in the United States and in other Western countries. In any case, about 20 million people in the United States have asthma today, including at least 6 million children, and 5,000 people a year die from it. Children in the inner cities seem to be especially hard hit, with exposure to cockroaches and diesel fumes suspected as the culprits. But the cause is not known for sure.

Worldwide, the disease has also increased. From 1985 to 2001, the prevalence rose 100 percent. About 300 million people have asthma, 255,000 die from it, and deaths could increase by 20 percent over the next 10 years, according to the World Health Organization. The problem is especially severe in developing countries, which are least able to provide the long-term intensive treatment that asthma requires.

Some of the apparent increases may not be real, but may have occurred because doctors got better at making the diagnosis. But increased reporting seems unlikely to account for all the new cases. Theories come and go, and when you come right down to it, no one really knows why some people develop asthma and others don’t.

In “The Asthma Epidemic,” an article published last week in The New England Journal of Medicine, doctors tried to sort out various theories about the causes of asthma and explain why rates have risen. But there are no clear-cut answers.

Like other chronic diseases, asthma is probably caused by multiple genes and environmental exposures, and it can have quite different causes in different people. About half the cases are thought to stem from allergies and the rest from other problems that can irritate and inflame the airways, causing them to close.

Genetic changes in the population cannot explain the increasing rates, though, because such changes occur too slowly to account for the rapid increases in asthma, the authors said, suggesting that environmental factors are more likely candidates. But what has changed enough in the environment to explain spiking asthma rates?

The authors of the article, from University Children’s Hospital in Munich, review many study findings. They report that one clear risk factor is secondhand tobacco smoke. Exposure to it does increase asthma risk in infants and small children. But how would that explain the increases, when over all, parents today smoke less than previous generations?

People frequently blame air pollution for causing asthma, but its role is not entirely clear. Pollution does makes asthma worse in people who already have the disease, but it’s not known whether pollution also makes asthma develop in the first place. And in any case, air pollution in the United States has decreased in the last few decades. Living in a place with high vehicle exhaust may make asthma worse, but the evidence is “relatively weak,” the researchers report.

Dust mites, microscopic insects that live in bedding and furniture, were long blamed for causing asthma to develop in infants and small children and have led to a booming industry of mattress covers, air filters and guilt-ridden parents tethered to dust mops and vacuum cleaners. But recent studies have questioned the connection. Once children have asthma, though, the mites and their droppings may make the symptoms worse.

Cat dander has become a complete puzzle, with some studies finding that exposure early in life leads to asthma, and others saying it protects against asthma. At this point, nobody knows which study to believe, but most experts agree that when people already have asthma, being around cats can make it worse.

Under some of the theories, I should have had the world’s worst asthma. Clearly, I had allergic tendencies, and the experts would have shuddered at my environment. I grew up in New York in a small apartment with parents who were heavy smokers, on a busy street with trucks rumbling by and a bus stop in front of the door. Buildings all around us burned coal. At times, we had a dog, a cat, parakeets and, briefly, a duck. It’s amazing that the pets survived the smoke. My mother was a decent housekeeper, but she wouldn’t have won any prizes. I never wheezed. Go figure.

Obesity and asthma have also been linked in some studies, but the link, if it exists, is not understood. Researchers say it is simply not a matter of asthmatic children growing fat because they cannot exercise. The weight gain can be first.

Nutrition is another mystery. Studies of fruits, vegetables, cereals, fatty acids, vitamins, minerals and antioxidants have been inconclusive, and little is known about the effects from what pregnant women eat. Experiments in which pregnant women avoided cow’s milk and eggs in hopes of preventing asthma in their infants did not work, and breast-feeding doesn’t prevent the disease, either.

One theory that has received attention recently is the “hygiene hypothesis,” the idea that children today are raised in homes that are too clean and that asthma is somehow caused by the lack of exposure to infections and bits of microbes early in life. Under this theory, germs are supposed to help the immune system develop normally, and without them the system may overreact to other substances in the environment, producing allergies and asthma.

There is some evidence to support the idea. Studies find that children raised on farms are less prone than others to asthma, maybe because they are exposed to plenty of microbes in barns and stables. But the connection is still not fully understood, and some viral infections clearly make asthma worse.

A related idea is that the increased use of antibiotics in recent decades contributes to asthma by changing the type of the bacteria that live in the gut. But that has not been proved. Some researchers have suggested that acetaminophen, used to treat pain and fever, may be linked to asthma. Its use increased in the 1980s, after pediatricians declared aspirin unsafe for children. But that theory has not been proved, either.

Ultimately, this new list of the usual suspects still doesn’t solve the mystery.

Gradually, my sons’ asthma diminished. Both became track and cross-country runners in high school, and now, as they have gone on to college and graduate school, the disease is rarely a problem. But it was a worry that hung over us for a long time.

As for the food allergies, we choose to assume that they last for life. The only way to find out for sure is called a “challenge,” in which you eat the risky food with doctors standing by to revive you in case it turns out that, gee, you’re still allergic to it after all. Somehow, I don’t think we’ll be signing up for that.

My sons have adrenaline kits to treat a severe reaction. Neither has ever needed it, and I know they don’t carry it around the way they’re supposed to when they go to restaurants.

Needless to say, I wish none of this had ever happened. But, based on what’s now known, could I have done anything to prevent it? Was it bad that we had cats when our children were born or that we later gave them away? Asthma transformed me and my husband from rather casual housekeepers into mop-wielding fanatics. I’m not sure it helped.

Suppose I had recognized that my own allergies meant that my children would be at risk. Would it have helped if I had then avoided eating nuts, peanuts and shellfish while I was pregnant and breast-feeding? I don’t think the answer is clear.

Similarly, I’m not convinced that it would have made a difference if I had been more cautious and methodical about introducing new foods in their first few years, though allergy groups recommend it. The only thing that seemed to do them any good was asthma medicine, and lots of it.

Because children who have even one parent with allergies and asthma have an increased risk of developing the same problems, it would be great if somebody could figure out a way to lower that risk in time to help my sons and the millions of other young people who were also caught in the asthma wave, when they decide to become parents. I am hoping, but I know it may be a problem with many solutions — or none.



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